Glass injection vials are a common type of pharmaceutical packaging in clinical use. Due to the special nature of pharmaceuticals, the state imposes strict requirements on packaging materials. The stability of glass makes it an excellent packaging choice for medicines that require long-term storage, so medicinal glass injection vials are widely used as clinical drug carriers.
Based on the new standards for pharmaceutical packaging materials, we explain the test items for medicinal glass injection vials and the corresponding testing instruments. Water resistance of glass grains is a routine test for glass products.
Testing Steps
- Crush the injection vials into pieces. Take an appropriate amount and place it in a mortar. Insert the pestle and strike it sharply once with a hammer.
- Transfer the crushed glass from the mortar onto the top sieve of a sieve stack. Repeat the above process.
- Vibrate the sieve stack with a sieve shaker (or shake manually) for 5 minutes.
- Transfer the glass grains that pass through Sieve A but remain on Sieve B into a weighing bottle, with a quantity of more than 10 g. Prepare 3 samples in total.
- Remove iron filings from each sample using a magnet, then transfer the grains into a 250 mL conical flask.
- Rinse the glass grains with anhydrous ethanol by swirling at least 6 times, using 30 mL each time, until the ethanol remains clear.
- Heat the conical flask with glass grains on a hot plate to remove residual anhydrous ethanol.
- Dry the sample in an oven, take it out, and cool it in a desiccator. The storage time shall not exceed 24 hours.
